Imipramine and Depression
نویسندگان
چکیده
منابع مشابه
Treatment by Imipramine of Deafness and Depression
aminoacid sequences in common which are thought to bind hormones to specific sequences of DNA and modify the gene transcription (Beato, 1989). The complex formed by the binding of a steroid with a receptor is translocated into the cell nucleus where it binds to DNA and influences the expression of genes So the activation in depression of the HPA axis involves various steps in producing excess C...
متن کاملA Comparative Study of Dothiepin (prothiaden) and Imipramine in Depression
In a single-blind, randomised, parallel-group study comparing the efficacy and tolerability of dothiepin (50-150 mg per day) and imipramine (50-150 mg per day) for 6 weeks, involving 60 adult patients with depression, it was observed that dothiepin was comparable to imipramine in terms of efficacy as assessed by Hamilton Rating Scale for depress ion, global scale for severty of illness and clin...
متن کاملParoxetine but not imipramine improved depression related outcomes in adolescents with DSM-IV major depression.
Patients 275 adolescents (mean age 15 y, 62% girls) who were medically healthy with a current episode of DSM-IV major depression for >8 weeks. Additional inclusion criteria were a total score of >12 on the Hamilton Depression Rating Scale (HDRS), a score of < 60 on the Children’s Global Assessment Scale, and a score of >80 on the Peabody Picture Vocabulary Test. Exclusion criteria included a cu...
متن کاملNorepinephrine and Serotonin Metabolism and Clinical Response to Combined Imipramine and Amitriptyline Therapy in Depression
The present study was aimed to find out the alteration of NE and 5HT systems in depression, if so in the same direction or not and to find out the clinical response to combined therapy of Imipramine and Amitriptyline, both tricyclic antidepressants. The study group consisted of 39 depressives as defined by I. C. D. 9 and 17 normal controls. Hamilton Depression Rating Scale was used to assess th...
متن کاملImipramine treatment and resiliency exhibit similar chromatin regulation in the mouse nucleus accumbens in depression models.
Although it is a widely studied psychiatric syndrome, major depressive disorder remains a poorly understood illness, especially with regard to the disconnect between treatment initiation and the delayed onset of clinical improvement. We have recently validated chronic social defeat stress in mice as a model in which a depression-like phenotype is reversed by chronic, but not acute, antidepressa...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1977
ISSN: 0007-1250,1472-1465
DOI: 10.1192/s0007125000012010